Posts by Hari Sadasivan

AMD Collaboration with the University of Michigan offers High Performance Open-Source Solutions to the Bioinformatics Community

Long read DNA sequencing technology is revolutionizing genetic diagnostics and precision medicine by helping us discover structural variants and assemble whole genomes. It also helps us study evolutionary relationships. Lower sequencing costs and high-throughput portable long read sequencers are revolutionizing precision medicine today. Long read sequencers from the top manufacturers including Oxford Nanopore (ONT) and PacBio, can produce reads that are much longer than previous generations of sequencers. However, long reads vary in length and are significantly more error prone than short reads. Sequence alignment (on CPUs) is one of the main bottlenecks in long read processing workflows.

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